Alpha Fertility Centre is located in Kuala Lumpur and is recognised for innovating several fertility firsts not just in Malaysia but also worldwide. Run by leading and highly trusted doctors and embryologists, the clinic is fully equipped to offer the latest full range of fertility treatment options including egg donation, egg banking, embryo cryopreservation, to name a few. These services are offered using revolutionary therapeutic laparoscopy and freezing technology.
Specialising in hysteroscopic surgery, In vitro fertilisation and laparoscopic surgery, the clinic pioneered the successful application of comparative genomic hybridisation for testing embryos with chromosomal inversion and translocation in 2011. It also developed the now widely used protocol and communication system for embryo transfer and the mathematical formula designed to help doctors on the appropriate quantum of ovarian drilling. The following are other achievements that the clinic is extremely proud of:
- The world’s 1st successful pregnancy and delivery following PGD-CGH diagnosis of chromosome inversion
- The world’s 1st reported successful pregnancy following the use of freeze-thawed sperm, freeze-thawed eggs, and freeze-thawed embryos
- The world’s 1st successful pregnancy and delivery in a patient with Müllerian agenesis (a woman born without a vagina)
- The world’s 1st reported delivery following the salvage of a presumably abnormal embryo
- The world’s 1st to demonstrate the importance of embryo transfer duration on pregnancy outcome.
Leading the world in several infertility treatment procedures, the clinic consistently achieves high pregnancy success rates that exceed top IVF centres around the world. It is also recognised for achieving 100% Freezing Survival Rate for eggs and embryos – thanks to its award-winning new freezing and thawing technologies.
Dr. Haris Hamzah is a fertility expert specializing in hysteroscopic surgery, In vitro fertilization, and laparoscopic surgery. His goal is to provide personalised treatment programmes that are tailored to address the specific and unique needs of each couple. Dr. Hamzah ensures that every step of the programme is thoroughly discussed and that every available treatment option is explored and explained in detail.
Obstetrics & Gynaecology
Blastocyst Transfer Program
A blastocyst transfer program is an assisted reproductive technique involving the implantation of a blastocyst into the womb. A blastocyst is an embryo that is around 5 to 6 days old that has already undergone cell division, producing surface and inner cells, which form the placenta and the fetus respectively. The embryo, moreover, is cultured in the lab from the fertilisation of sperm and egg cells and is expected to be capable of creating genes. After the blastocyst forms, it can be implanted into the uterus, where it is expected to hatch and grow into a fetus to full term. This procedure is not recommended for women with endometriosis.
Egg donation refers to the process of a woman’s voluntary contribution of her eggs for conception or medical research. If it’s for conception, the woman may be the partner and give her eggs for in vitro fertilisation or be a known or anonymous egg donor for a couple. Egg donors go through a very rigid screening process including analysis of their genetic profiles, lifestyles, and medical and family histories. They would also undergo gynecological examinations including determining the quality of egg cells they produce. To harvest the eggs, a laparoscopic procedure is often carried out to get them from the ovaries.
Gamete Intrafallopian Transfer (GIFT)
The gamete intrafallopian transfer (GIFT) is an assisted reproductive procedure that involves the removal of egg cells and then mixing the egg and sperm before they are injected into the fallopian tube, where the fertilisation is expected to take place. For this to work, it is essential that the woman has good-quality fallopian tubes, which can be assessed through an X-ray or a laparoscope procedure. Laparoscopy can also be used to collect the egg cells directly from the ovaries. The egg and the sperm cells are then placed in a catheter where they are combined before they are introduced into the tubes. The procedure is recommended for couples with unexplained infertility who have not had success with In Vitro Fertilisation procedure.
In Vitro Fertilisation (IVF)
In vitro fertilisation refers to a variety of conception techniques involving the culture of both the egg and sperm in a lab. It involves different steps including egg production stimulation, egg retrieval, fertilisation, and embryo transfer. Both the egg and sperm can come from the couple, or one or both may be donated by an anonymous or known donor. If the lab’s fertilisation is successful, the embryo is transferred into the woman’s uterus or injected into a gestational carrier (surrogate) if the woman partner has a lesser chance of bringing the baby to a full term. The entire cycle, including the fertilisation, is often completed within two weeks after harvest.
Intra-Uterine Insemination (IUI)
The intra-uterine insemination (IUI) is an assisted conception procedure wherein the sperm cells are injected into the uterus to stimulate fertilisation. IUI is recommended for both men and women who have infertility issues such as scarring that prevent the union of the egg and sperm cells, as well as low sperm count. The goal is to increase the chances of one of the sperms uniting with an egg by letting them be as close as possible. During the procedure, a semen sample is collected, and the sperm is seperated from the fluid before it is transferred into a catheter. The catheter will then be inserted into the uterus.
Intracytoplasmic Sperm Injection (ICSI)
Intracytoplasmic sperm injection (ICSI) is an assisted reproductive technique where only one sperm is chosen and injected into the harvested egg cell. It is often recommended for males who suffer from poor sperm motility or volume as well as those who have infertility issues. First, the egg cell is collected and placed in a tube. Next, sperm cells are obtained, and the best one is chosen for fertilisation. This sperm cell is injected very gently into the cytoplasm of the egg cell. The next day, the doctor checks if fertilisation has occurred. If it is, the embryo is then transferred to the woman or a gestational carrier.
Laparoscopic (Key-Hole) Surgery
Ovaries are prone to developing cysts, and although they may not immediately pose a threat, they may have to be removed if they are already causing pain and bleeding, if they are suspected to be cancerous, or if they lead to complications such as a difficult conception or pregnancy. To remove the cysts, a laparoscopic surgery may be performed wherein only small incisions are made, hastening the healing and reducing the swelling. A small incision is created in the lower part of the belly button and a tube with a camera called a laparoscope is inserted to allow the doctor to see and locate the cyst on a computer screen. Once the cyst is located, additional small incisions are made, and tiny surgical tools are used to remove them. Tissue samples may also be collected for cancer screening or biopsy.
Pre-Implantation Genetic Diagnosis
The pre-implantation genetic diagnosis (PGD) is a genetic test performed on the embryo to determine if the cells carry genes that are considered defective, which may then lead to disorders when the child is born. This is carried out following in vitro fertilisation, in which the egg and sperm cells have already been harvested and fertilised in the lab. Dr. Haris Hamzah waits for about three days when the embryo has already started cell division. During the test, sample cells are obtained and evaluated for different inherited disorders. If there are none, the embryo is implanted into the womb. Otherwise, it is destroyed.